19.11.2015
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Dissertation: Structural Studies of Nano-Sized Supramolecular Assemblies

Time:

27.11.2015 12:00 — 15:00


Location: Ylistonrinne, KEM4
M.Sc. Filip Topic defends his doctoral dissertation in Organic Chemistry "Structural Studies of Nano-sized Supramolecular Assemblies". Opponent Professor Neil Champness (University of Nottingham, UK) and custos Academy Professor Kari Rissanen (University of Jyväskylä)

Filip Topic, kuva Sandra KaabelM.Sc. Filip Topic defends his doctoral dissertation in Organic Chemistry "Structural Studies of Nano-sized Supramolecular Assemblies". Opponent Professor Neil Champness (University of Nottingham, UK) and custos Academy Professor Kari Rissanen (University of Jyväskylä)

Abstract

In the thesis, the structural studies of a number of supramolecular assemblies are presented, with the results obtained grouped into four different topics. In the first chapter, two studies are presented, one rationalizing the unexpected stereochemical outcome of a subcomponent self-assembly reaction, while the other deals with expanding a class of water-soluble cage complexes and its host-guest chemistry, again prepared by the same approach. The second chapter deals with the self-assembly of chiral pyridine-based ligands with palladium and platinum, focussing mostly on the diastereoselective self-sorting upon their formation. In two cases, however, the unexpected outcome of the self-assembly demanded a more thorough investigation to solve the chemical puzzles that emerged. In the third chapter, structural analysis of two ion receptor systems is presented. First, two similar ion triplet receptor molecules based on (thio)urea are studied, with the crystallographic analysis shedding light both on the shared aspects of their behaviour as well as their differences. Next, strong and selective binding of fluoride in water by an unorthodox receptor is studied and rationalized, also with the help of crystallography. The final chapter is devoted to two cases of demanding crystallographic analysis. In the first example, the challenging part was the modelling of the extensively disordered parts of the molecule. In the second example, a crystal engineering approach was adopted to prepare a solid form of the molecule of interest more amenable to crystallographic analysis.

More information

Filip Topic

None

filip.f.topic@jyu.fi